Angie Xiu

Computational biology · The Xiu Lab

I build open-source computational tools that help make sense of the genetics behind rare diseases, from interpreting unknown variants to designing potential therapies. If you're curious about my work (or if you're working on something similar), I'd love to hear from you!

Selected work

• ChanVar
  Interpreting unknown CACNA1A variants, including whether a change makes the calcium channel over- or under-active.
• AlleleSelect
  Designing antisense therapies that silence the faulty copy of a gene while sparing the healthy one.
• SigVigil
  Surfacing how migraine medications affect adolescent girls, a group clinical trials tend to overlook.
• DermEquity

  Measuring and reducing bias in medical AI, validated in skin-cancer screening.